QuantaMetrics Online Brochure 3

Experimetria

DATA ACQUISITION SYSTEMS

HAEMOSYS: Hæmodynamic whole heart research
ISOSYS: Isolated tissue/organ research
NEUROSYS: Evoked or spontaneous electrical potentials (EEG, EMG, EP) of CNS in-vivo or in-vitro
INTRASYS: In-vitro intracellular action potentials evoked by electrical stimulation or contractile force
CARDIOSYS: Cardiac output for rats, rabbits and dogs
Contact QuantaMetrics for demo software.

Experimetria's HAEMOSYS is a software and hardware system for the acquisition and analysis of hemodynamic data. The hardware is capable of accepting up to eight analog signals simultaneously. The software acquires, processes and graphically displays data for the following biological signals:

CLICK IMAGE TO ENLARGE

LVP left ventricular pressure
BP venous and/or anterial blood pressure
EEG electrocardiogram
SG strain gauge—force/displacement
TEMP temperature
RESP respiratory rate
GEN any pulsed signal
NPGEN any non-pulsed (analog) signal

Acquired data is interpreted to generate values for heart rate, systolic, mean and dystolic blood pressure, as well as differentiated curves with positive and negative trends. In addition, the following special parameters can be derived from the data:

LVP time to peak tension, relaxation time at 64%, 100% and a user-defined value, end distolic pressure
BP pulse pressure, ejection time
BF stroke volume
ECG Rmax, Pmax, Tmax, R-R duration, P-Q duration, Q-R-S duration, Q-T duration S-T segment elevation

Other parameters can be calculated, such as conductivity based on mean blood flow and mean blood pressure. Data can be stored and analyzed off-line, and exported to other analysis software such as Excel.

The system includes an 8-channel interface card (ISY-100), interface cable, computer interface board (ISY-101), rack and power supply (RPW-04), software and Pentium computer with monitor and mouse.

TYPICAL SYSTEM FOR IN VIVO HAEMODYNAMICS
HG (X2)	Bridge amplifier for measurement of blood pressure
BPR-01 (X2)	Reusable blood pressure transducer with dome
ECG	Electrocardiograph amplifier with digital heart rate display
SG	Bridge amplifier for measurement of contractile force (strain gauge)
FSG-02	Implantable/sewable force/displacement transducers, force range 0-400g, sizes: small (5x10mm), medium (6x15mm), large (9x17mm)
LH	Respiratory rate meter (2-120 p/min)
FLH-01	Respiration sensors, sizes: rat (2.5mm od.), small cat (6mm od.), large cat (7mm od.), small dog (10mm od.), large dog (12mm od.)
TH	Temperature meter (20-40/100 deg. C)
RTH-01	Stick temperature probe (rectal or oral), sizes: small (2mm od.), large (3mm od.)
RPW-08	Rack and power supply for eight amplifiers (110V/50Hz)
HAEMOSYS	Software and hardware system for hemodynamic data acquisition and analysis. Includes 8-channel interface card (ISY-100), interface cable, computer interface board (ISY-101), rack and power supply (RPW-04), Pentium computer with monitor and mouse
Optional devices: Transonic flowmeter to measure blood flow

Experimetria's ISOSYS is a software and hardware system for data acquisition and analysis of isolated tissue/organ investigations. The hardware is capable of accepting up to eight analog signals simultaneously. The software acquires, processes and graphically displays data for pulsed and non-pulsed (analog) signals. The system works as an "intelligent" chart recorder on-line, and can calculate the following values:
CLICK IMAGE TO ENLARGE	dF/dt curve (F=force, t=time) maximum development rate (+dF/dt) maximum relaxation velocity (-dF/dt) pulse cycle min and max values mean value and contraction rate half contraction time time to peak tension contraction time constant (cycle) contraction force values zero and minimum derivative values area under the curve and slope user-defined relaxation values latency period relaxation time and total duration
After data is acquired and stored, "dose-response" values can be calculated, including ED50 and pD2 values; pA2 or pD2 values can be displayed and printed graphically. Data can also be exported to other analysis software such as Excel. The system includes an 8-channel interface card (ISY-100), interface cable, computer interface board (ISY-101), rack and power supply (RPW-04), software and Pentium computer with monitor and mouse. Typical system for in vitro small vessel reactivity measurement Typical system for in vitro tissue/small organ studies
CLICK IMAGE TO ENLARGE CLICK IMAGE TO ENLARGE	Experimetria's NEUROSYS is a software and hardware system for data acquisition and analysis of evoked or spontaneous electrical potentials of CNS in-vitro or in-vivo. The system acquires and graphically displays analog signals for storage and analysis. As an example, the following data can be derived from signals evoked electrically, mechanically, by light or by sound: total signal amplitude amplitude of individual waves time interval from trigger to first, second or third positive peak time interval from trigger to first, second or third negative peak time interval from trigger to one of two markers time interval between two markers In addition, the software calculates values for EEG parameters following Furier analysis, including total or relative power and total or relative amplitude.
The system includes an 8-channel interface card (ISY-100), interface cable, computer interface board (ISY-101), rack and power supply (RPW-04), software and Pentium computer with monitor and mouse. Typical system for evoked potentials on brain slice
CLICK IMAGE TO ENLARGE	Experimetria's INTRASYS is a software and hardware system designed for in-vitro intracellular signal data acquisition and analysis. The action potential (AP) and force (F) analog signals are acquired and displayed simultaneously. The system also features a stimulator, and the acquisition display can be used as a storage oscilloscope for the analysis of the following values:
ACTION POTENTIAL RP resting potential TOP take-off potential APA(RP) action potential amplitude referenced to RP APA(MDP) action potential referenced to MDP MDP maximum diastolic potential (greatest negative point on curve) OS overshoot potential CT time between leading edge of trigger and leading edge of curve APD time period corresponding to 10%, 25%, 50%, 75% or 90% of return (user-defined) +dT positive maximum of derivative signal -dT negative maximum of derivative signal FORCE RT resting tension TT twitch tension TTP time to peak tension T time period corresponding to 25%, 50% or 90% of return (user-defined) DC duration of contraction DT time period from stimulus breakthrough to 5% point of the force signal DTt time period from peak of the AP signal to 5% point of the force signal +dT positive maximum of derivative signal -dT negative maximum of derivative signal Data can be exported to other analysis software such as Excel. The system includes a 2-channel interface card (NTR-100), computer interface board (ISY-101), rack and power supply (RPW-04), and software. Computer required but not included. Typical transmembrane action potential measuring system
Experimetria's CARDIOSYS, together with the Model CO-101 Cardiac Output Device, make up an advanced system for in-vivo data acquisition, storage and analysis of cardiac output (CO). CO is measured using the thermodilution method, and the following values are acquired and calculated:
CLICK ON IMAGE TO ENLARGE	blood temperature indicator temperature dTmax maximum temperature difference heart rate (beat/min) blood pressure: systolic, mean and diastolic (mmHg) stroke volume (ml/beat) cardiac output (ml/min) cardiac output index (ml/min/Kg) MBP X HR (mmHgbeat/min) MBP/CO (mmHgml/min) MBP X CO (ml/min*mmHg)
Calculated parameters are stored as trends during an experiment, and markers with text can be added to the data. CO trending is calculated continuously between experiments, and up to four thermodilution curves can be displayed simultaneously. Data can be stored and analyzed off-line, printed, and exported to other analysis software such as Excel. The system includes a blood pressure transducer (BPR-02), thermodilution probe (PTH-01), catheter temperature probe (RCH-01), foot pedal, analog and digital boards, and Pentium computer with monitor and mouse.

Top of Page | Home Page | Contact QuantaMetrics
Copyright © 1999-2008 QuantaMetrics Inc. All Rights Reserved.
All trademarks or registered trademarks per their respective companies and used by permission.
Specifications subject to change without notice.